Amedeo's Top 20

Amedeo Smart

Independent Medical Education


15 October 2018

Multidisciplinary Journal Club

  1. Van Der Meeren O, Hatherill M, Nduba V, Wilkinson RJ, et al.
    Phase 2b Controlled Trial of M72/AS01E Vaccine to Prevent Tuberculosis.
    N Engl J Med 2018.

  1. .
    Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.
    N Engl J Med 2018.

  2. Bath PM, Woodhouse LJ, Appleton JP, Beridze M, et al.
    Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial.
    Lancet 2017.

  3. Hassager C, Nagao K, Hildick-Smith D.
    Out-of-hospital cardiac arrest: in-hospital intervention strategies.
    Lancet 2018;391:989-998.

  4. Forner A, Reig M, Bruix J.
    Hepatocellular carcinoma.
    Lancet 2018.

  1. Thiele EA, Marsh ED, French JA, Mazurkiewicz-Beldzinska M, et al.
    Cannabidiol in patients with seizures associated with Lennox-Gastaut syndrome (GWPCARE4): a randomised, double-blind, placebo-controlled phase 3 trial.
    Lancet 2018;391:1085-1096.

  2. Eyre DW, Sheppard AE, Madder H, Moir I, et al.
    A Candida auris Outbreak and Its Control in an Intensive Care Setting.
    N Engl J Med 2018;379:1322-1331.

  3. Geserick M, Vogel M, Gausche R, Lipek T, et al.
    Acceleration of BMI in Early Childhood and Risk of Sustained Obesity.
    N Engl J Med 2018;379:1303-1312.

  4. Stone GW, Lindenfeld J, Abraham WT, Kar S, et al.
    Transcatheter Mitral-Valve Repair in Patients with Heart Failure.
    N Engl J Med 2018.

  5. Rehermann B, Thimme R.
    Insights From Antiviral Therapy into Immune Responses to HBV and HCV Infection.
    Gastroenterology 2018.

  1. Belperio PS, Shahoumian TA, Loomis TP, Mole LA, et al.
    Real-world Effectiveness of Daclatasvir plus Sofosbuvir and Velpatasvir/Sofosbuvir in Hepatitis C Genotype 2 and 3.
    J Hepatol 2018.

  2. Papi A, Vestbo J, Fabbri L, Corradi M, et al.
    Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial.
    Lancet 2018;391:1076-1084.

  3. Kedhi E, Fabris E, van der Ent M, Buszman P, et al.
    Six months versus 12 months dual antiplatelet therapy after drug-eluting stent implantation in ST-elevation myocardial infarction (DAPT-STEMI): randomised, multicentre, non-inferiority trial.
    BMJ 2018;363:k3793.

  4. Gucalp A, Traina TA, Eisner JR, Parker JS, et al.
    Male breast cancer: a disease distinct from female breast cancer.
    Breast Cancer Res Treat 2018.

  5. Boeve LMS, Hulshof MCCM, Vis AN, Zwinderman AH, et al.
    Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Cli
    Eur Urol 2018.

  1. Dziadzko V, Clavel MA, Dziadzko M, Medina-Inojosa JR, et al.
    Outcome and undertreatment of mitral regurgitation: a community cohort study.
    Lancet 2018;391:960-969.

  2. Botha J, Conradie F, Etheredge H, Fabian J, et al.
    Living donor liver transplant from an HIV-positive mother to her HIV-negative child: opening up new therapeutic options.
    AIDS 2018;32:F13-F19.

  3. Jeter JM, Bowles TL, Curiel-Lewandrowski C, Swetter SM, et al.
    Chemoprevention agents for melanoma: a path forward into phase 3 clinical trials.
    Cancer 2018.

  4. Dohner H, Dolnik A, Tang L, Seymour JF, et al.
    Cytogenetics and gene mutations influence survival in older patients with acute myeloid leukemia treated with azacitidine or conventional care.
    Leukemia 2018.

  5. Moskowitz CH, Walewski J, Nademanee A, Masszi T, et al.
    Five-year PFS from the AETHERA trial of brentuximab vedotin for Hodgkin lymphoma at high risk of progression or relapse.
    Blood 2018.


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