Amedeo's Top 20

Amedeo Smart

Independent Medical Education


27 August 2018

Multidisciplinary Journal Club

  1. Emu B, Fessel J, Schrader S, Kumar P, et al.
    Phase 3 Study of Ibalizumab for Multidrug-Resistant HIV-1.
    N Engl J Med 2018;379:645-654.

  1. O'Neil PM, Birkenfeld AL, McGowan B, Mosenzon O, et al.
    Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial.
    Lancet 2018.

  2. Arbour KC, Mezquita L, Long N, Rizvi H, et al.
    Impact of Baseline Steroids on Efficacy of Programmed Cell Death-1 and Programmed Death-Ligand 1 Blockade in Patients With Non-Small-Cell Lung Cancer.
    J Clin Oncol 2018.

  3. Song X, Jensen MO, Jogini V, Stein RA, et al.
    Mechanism of NMDA receptor channel block by MK-801 and memantine.
    Nature 2018;556:515-519.

  4. Antonio MB, Cuba GT, Vasconcelos RP, Alves APPS, et al.
    Natural experiment of syphilis treatment with doxycycline or benzathine penicillin in HIV-infected patients.
    AIDS 2018.

  1. Rimawi M, Ferrero JM, de la Haba-Rodriguez J, Poole C, et al.
    First-Line Trastuzumab Plus an Aromatase Inhibitor, With or Without Pertuzumab, in Human Epidermal Growth Factor Receptor 2-Positive and Hormone Receptor-Positive Metastatic or Locally Advanced Breast Cancer (PERTAIN): A Randomized,
    J Clin Oncol 2018.

  2. Litton JK, Rugo HS, Ettl J, Hurvitz SA, et al.
    Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation.
    N Engl J Med 2018.

  3. Hu Y, Zong G, Liu G, Wang M, et al.
    Smoking Cessation, Weight Change, Type 2 Diabetes, and Mortality.
    N Engl J Med 2018;379:623-632.

  4. Gray ER, Bain R, Varsaneux O, Peeling RW, et al.
    p24 revisited: A landscape review of antigen detection for early HIV diagnosis.
    AIDS 2018.

  5. Hoffman KE, Voong KR, Levy LB, Allen PK, et al.
    Randomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer.
    J Clin Oncol 2018.

  1. McAninch EA, Rajan KB, Miller CH, Bianco AC, et al.
    Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism: A Systematic Review and Meta-Analysis.
    J Clin Endocrinol Metab 2018.

  2. Dabaja BS, Hoppe BS, Plastaras JP, Newhauser W, et al.
    PROTON THERAPY FOR ADULTS WITH MEDIASTINAL LYMPHOMAS: THE INTERNATIONAL LYMPHOMA RADIATION ONCOLOGY GROUP (ILROG) GUIDELINES.
    Blood 2018.

  3. Vatner RE, Niemierko A, Misra M, Weyman EA, et al.
    Endocrine Deficiency as a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors.
    J Clin Oncol 2018.

  4. Devarakonda S, Rotolo F, Tsao MS, Lanc I, et al.
    Tumor Mutation Burden as a Biomarker in Resected Non-Small-Cell Lung Cancer.
    J Clin Oncol 2018.

  5. Marinovich ML, Hunter KE, Macaskill P, Houssami N, et al.
    Breast Cancer Screening Using Tomosynthesis or Mammography: A Meta-analysis of Cancer Detection and Recall.
    J Natl Cancer Inst 2018.

  1. Kirchgesner J, Lemaitre M, Carrat F, Zureik M, et al.
    Risk of Serious and Opportunistic Infections Associated With Treatment of Inflammatory Bowel Diseases.
    Gastroenterology 2018;155:337-346.e10.

  2. Costentin C, Layese R, Bourcier V, Cagnot C, et al.
    Compliance With Hepatocellular Carcinoma Surveillance Guidelines Associated With Increased Lead-time Adjusted Survival of Patients With Compensated Viral Cirrhosis.
    Gastroenterology 2018.

  3. Malan V, Bussieres L, Winer N, Jais JP, et al.
    Effect of Cell-Free DNA Screening vs Direct Invasive Diagnosis on Miscarriage Rates in Women With Pregnancies at High Risk of Trisomy 21: A Randomized Clinical Trial.
    JAMA 2018;320:557-565.

  4. Wilson MJA, MacArthur C, Hewitt CA, Handley K, et al.
    Intravenous remifentanil patient-controlled analgesia versus intramuscular pethidine for pain relief in labour (RESPITE): an open-label, multicentre, randomised controlled trial.
    Lancet 2018.

  5. Brownlee WJ, Miszkiel KA, Tur C, Barkhof F, et al.
    Inclusion of optic nerve involvement in dissemination in space criteria for multiple sclerosis.
    Neurology 2018.


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