Amedeo's Top 20

Amedeo Smart

Independent Medical Education

02 July 2018

Multidisciplinary Journal Club

  1. Jaber S, Paugam C, Futier E, Lefrant JY, et al.
    Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial.
    Lancet 2018.

  1. Socinski MA, Jotte RM, Cappuzzo F, Orlandi F, et al.
    Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC.
    N Engl J Med 2018;378:2288-2301.

  2. Gizzi AS, Grove TL, Arnold JJ, Jose J, et al.
    A naturally occurring antiviral ribonucleotide encoded by the human genome.
    Nature 2018.

  3. Svensson EM, Svensson RJ, Te Brake LHM, Boeree MJ, et al.
    The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis.
    Clin Infect Dis 2018;67:34-41.

  4. Banham GD, Flint SM, Torpey N, Lyons PA, et al.
    Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.
    Lancet 2018.

  1. DiMeglio LA, Evans-Molina C, Oram RA.
    Type 1 diabetes.
    Lancet 2018;391:2449-2462.

  2. Yu L, Petyuk VA, Gaiteri C, Mostafavi S, et al.
    Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia.
    Ann Neurol 2018.

  3. Kayama T, Sato S, Sakurada K, Mizusawa J, et al.
    Effects of Surgery With Salvage Stereotactic Radiosurgery Versus Surgery With Whole-Brain Radiation Therapy in Patients With One to Four Brain Metastases (JCOG0504): A Phase III, Noninferiority, Randomized Controlled Trial.
    J Clin Oncol 2018.

  4. da Silva JA, Tecuapetla F, Paixao V, Costa RM, et al.
    Dopamine neuron activity before action initiation gates and invigorates future movements.
    Nature 2018;554:244-248.

  5. Emsley R, Nuamah I, Gopal S, Hough D, et al.
    Relapse After Antipsychotic Discontinuation in Schizophrenia as a Withdrawal Phenomenon vs Illness Recurrence: A Post Hoc Analysis of a Randomized Placebo-Controlled Study.
    J Clin Psychiatry 2018;79.

  1. Champenois K, Seng R, Persoz A, Essat A, et al.
    Recent trends in sexual behaviours among MSM followed since primary HIV-1 infection.
    AIDS 2018.

  2. Tliba O, Panettieri RA.
    Paucigranulocytic asthma: The uncoupling of airway obstruction from inflammation.
    J Allergy Clin Immunol 2018.

  3. Kao LS, Ball CG, Chaudhury PK.
    Evidence-based Reviews in Surgery: Early Cholecystectomy for Cholecystitis.
    Ann Surg 2018.

  4. Singh S, Proudfoot JA, Dulai PS, Jairath V, et al.
    No Benefit of Concomitant 5-Aminosalicylates in Patients With Ulcerative Colitis Escalated to Biologic Therapy: Pooled Analysis of Individual Participant Data From Clinical Trials.
    Am J Gastroenterol 2018.

  5. Nagpal SJS, Sharma A, Chari ST.
    Autoimmune Pancreatitis.
    Am J Gastroenterol 2018.

  1. Lam CSP, Voors AA, de Boer RA, Solomon SD, et al.
    Heart failure with preserved ejection fraction: from mechanisms to therapies.
    Eur Heart J 2018.

  2. Al-Khaifi A, Rudling M, Angelin B.
    An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers.
    Gastroenterology 2018.

  3. Musso G, Cassader M, Paschetta E, Gambino R, et al.
    Bioactive lipid species and metabolic pathways in progression and resolution of Non-Alcoholic Steatohepatitis.
    Gastroenterology 2018.

  4. Van Stappen T, Vande Casteele N, Van Assche G, Ferrante M, et al.
    Clinical relevance of detecting anti-infliximab antibodies with a drug-tolerant assay: post hoc analysis of the TAXIT trial.
    Gut 2018;67:818-826.

  5. Cao B, Cho RY, Chen D, Xiu M, et al.
    Treatment response prediction and individualized identification of first-episode drug-naive schizophrenia using brain functional connectivity.
    Mol Psychiatry 2018.


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