The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model. Zhou Z, Lu Y, Li P, Liu X, et al. PLoS Biol 2026;24:e3003603.

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Amedeo Smart

Independent Medical Education

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Zhou Z, Lu Y, Li P, Liu X, et al. The lipid-metabolic enzyme HSD17B12 drives lysosomal degradation of PD-L1 potentiating anti-tumor immunity in a mouse model. PLoS Biol 2026;24:e3003603.
PMID: 41592073