ApoE4 lowers the ptau217 threshold for tau aggregation and spread in an allele dose-dependent manner. Steward A, Dewenter A, Hirsch F, Roemer-Cassiano SN, et al. Brain 2025 Dec 18:awaf463. doi: 10.1093.

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Steward A, Dewenter A, Hirsch F, Roemer-Cassiano SN, et al. ApoE4 lowers the ptau217 threshold for tau aggregation and spread in an allele dose-dependent manner. Brain 2025 Dec 18:awaf463. doi: 10.1093.
PMID: 41410687