OTUB1 antagonizes TRIM21 to induce deubiquitination of SPHK1 and promote the progression of hepatocellular carcinoma. Sun C, Cai S, Yang J, Du M, et al. Oncogene 2025 Aug 30. doi: 10.1038/s41388-025-03556.

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Amedeo Smart

Independent Medical Education

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Sun C, Cai S, Yang J, Du M, et al. OTUB1 antagonizes TRIM21 to induce deubiquitination of SPHK1 and promote the progression of hepatocellular carcinoma. Oncogene 2025 Aug 30. doi: 10.1038/s41388-025-03556.
PMID: 40885853