A noncoding mutation in the NOTCH1 gene initiates oncogenic NOTCH signaling via wild-type NICD stabilization in CLL. Guo M, Memis T, Ehrmann AS, Pittrof A, et al. Blood 2025;146:1936-1949.

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Amedeo Smart

Independent Medical Education

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Guo M, Memis T, Ehrmann AS, Pittrof A, et al. A noncoding mutation in the NOTCH1 gene initiates oncogenic NOTCH signaling via wild-type NICD stabilization in CLL. Blood 2025;146:1936-1949.
PMID: 40638689