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Krijbolder DI, Verstappen M, van Dijk BT, Dakkak YJ, et al. Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial Lancet 2022;400:283-294.
PMID: 35871815

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